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Abdominal trauma or obstetrical manipulation.Amniocentesis, chorionic villus sampling (CVS) and percutaneous umbilical blood sampling (PUBS).Prophylaxis at 26 to 28 weeks gestation Administer within 72 hours of suspected or proven exposure to Rh-positive red blood cells resulting from:.This may be determined by use of qualitative or quantitative tests for fetal-maternal hemorrhage. Postpartum (if the newborn is Rh-positive) Administer within 72 hours of delivery.Īdditional doses of RhoGAM are indicated when the patient has been exposed to > 15 mL of Rh-positive red blood cells. * : After delivery, obstetric complications, and/or invasive procedures, the volume of the fetal-maternal hemorrhage must be determined to calculate the exact dose of RhoGAM required.
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Pregnancy and other obstetrical conditions Dose ( 2.1) DoseĪdminister 20 µg of RhoGAM per mL of Rh-positive red blood cell exposure, rounding up to the next whole syringe. Transfusion of Rh-incompatible blood or blood products ( 2.1)Īdminister within 72 hours of suspected or proven exposure to Rh-positive red blood cells.
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RhoGAM may be administered if MICRhoGAM is not available. If antepartum prophylaxis is indicated, it is essential that the mother receive a postpartum dose if the infant is Rh-positive.Īctual or threatened termination of pregnancy (spontaneous or induced) up to and including 12 weeks gestation Administer within 72 hours Obstetric complications/ invasive procedures beyond 13 weeks gestation.Prophylaxis at 26 to 28 weeks gestation Administer within 72 hours of suspected or proven exposure to Rh-positive red blood cells.Postpartum (if the newborn is Rh-positive) Administer within 72 hours of deliveryĪdditional doses of RhoGAM are indicated when the patient has been exposed to > 15 mL of Rh-positive red blood cells. * After delivery, obstetric complications, and/or invasive procedures, the volume of the fetal-maternal hemorrhage must be determined to calculate the exact dose of RhoGAM required. Pregnancy and other obstetrical conditions ( 2.1) Dose